Drug Discovery
High-throughput screening needs a cell supply that doesn't run out or drift between lots. Cell Biologics' immortalized lines are derived from our validated primary cell backgrounds across most tissue types and species in the catalogue, giving unlimited expansion with lot-to-lot consistency.
Reporter-modified variants (GFP, RFP, luciferase) are available on the same immortalized backgrounds for high-content and bioluminescent screening formats.
Drug Discovery — frequently asked questions
How do immortalized lines compare to primary cells for screening?
Immortalized lines trade some in-vivo phenotypic fidelity for unlimited expansion and consistent behaviour across lots — the property that matters most at screening scale. For assays sensitive to phenotype drift, our primary cells remain the validated reference.
Can I get both a primary and immortalized version of the same cell type for validation?
In most cases, yes — many of our immortalized lines are derived directly from a primary line already in the catalogue. Contact us to confirm a matched pair for your specific cell type.
Not sure which model fits your assay?
Talk to a cell biologist — we help scope isolation, media, and passage strategy at no cost.
