APPLICATION

Cell-Based Assays

Live-cell imaging and high-content screening need a stable, bright reporter signal that doesn't perturb the underlying biology. Cell Biologics offers GFP-, RFP-, and luciferase-expressing variants across most primary and immortalized lines in the catalogue.

GFP and RFP variants suit fluorescence microscopy and flow-based assays; luciferase variants are validated for in vivo bioluminescent imaging following xenograft or engraftment studies.

496 products
6 species
8 cell types
ISO 9001 quality system

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Cell-Based Assays — frequently asked questions

Which reporter should I choose — GFP, RFP, or luciferase?

GFP and RFP are the standard choice for in vitro fluorescence imaging and flow cytometry; luciferase is the choice for in vivo bioluminescent tracking, since it doesn't require external excitation light and has lower tissue background.

Does the reporter affect the cell's baseline biology?

Reporter lines are validated against their unmodified parental line for growth rate and, where applicable, differentiation potential, before release. Full validation data is available on request.

Not sure which model fits your assay?

Talk to a cell biologist — we help scope isolation, media, and passage strategy at no cost.